Neutralising IgG antibodies are the antibodies that target the spike of the SARS-CoV-2 virus so that it cannot enter the cell it is trying to infect and therefore the virus cannot replicate. They can also help stop the virus from changing, which are known as conformational changes that help it improve how it enters and replicates within a cell. They are different from binding antibodies which they work alongside with, which bind to the virus and then alert your immune system so it can produce white blood cells to fight the virus off. Neutralising antibodies are made by B-cells which are made in your bone marrow
